Abstract: Research advances on the application of pyrophyllite in fields of superhard material, refractories, ceramic industry and environmental remediation are reviewed. The research status, challenges and prospects of using pyrophyllite as a sealing and pressure-transmitting medium in the synthesis of superhard materials are mainly discussed. Due to its unique structure and properties, especially the thermal behavior, pyrophyllite plays an irreplaceable role in synthesizing superhard materials, rendering it a strategic resource with superiority in China. Research and development of pyrophyllite-based hybrid sealing and pressure-transmitting medium is a research area that needs to pay more attention and devotion in the future.