Abstract: High purity quartz (HPQ), as a key basic material for strategic emerging industries, is essential to ensure the security of China's resource supply. In this paper, the pegmatite-type HPQ was selected as the research object, and then a whole chain survey and evaluation system for pegmatite-type HPQ was first established in China. This system included metallogenic prospect prediction, survey area delineation, accurate sample collection, sample pretreatment, deep beneficiation and impurity removal, deep chemical purification, and analysis of product. Moreover, the North Qinling region was chosen to proof of the concept. It was found that 11 pegmatite dikes could produce 4N level (SiO₂ content ≥ 99.99%), even 4N5 level (SiO₂ content ≥ 99.995%) of HPQ from 350 pegmatite dikes in this area. The methodological system realized the precise investigation and evaluation of the pegmatite-type HPQ, and the hierarchical evaluation according to the resource characteristics. More importantly, the development and utilization program and product application analysis for different veins were effectively established, which fully ensured that high quality resources were used in the terminal market. These findings would provide a reference for the mining discovery of HPQ, and strongly support the secure supply of key materials for the strategic emerging industries in China.