Abstract: The demand of photovoltaic quartz sand increases sharply with the rapid development of photovoltaic industry. In order to fully use abundant low-quality quartz in our country to prepare photovoltaic quartz sand, the systematic process mineralogy of quartz sand (SiO₂ and Fe₂O₃ were 97.228% and 1331.69 μg/g, respectively) from Hanzhong, Shaanxi Province, was studied to investigate the occurrence of iron-containing impurities. The results showed that the occurrence state of Fe was complex, mainly existing in hematite, iron-bearing rutile, iron-stained mica and tourmaline. These impurities were removed through a combined process of magnetic separation-scrubbing-flotation-acid leaching, finally the high-quality photovoltaic quartz sand was obtained with SiO₂ and Fe₂O₃ being of 99.949% and 62.41 μg/g, respectively. Overall, the removal of Fe₂O₃ was 95.31%, with the contribution from magnetic, scrubbing, flotation and acid leaching separation being of 43.87%, 3.73%, 21.18% and 26.53%, respectively. Therefore, the application of the purification technology developed in this study can promote the development of photovoltaic industry in China, achieving better social and economic benefits and providing technical supports for the two-carbon policy.