Abstract: High-purity quartz is widely used in high-tech fields, and is a key basic material for strategic emerging industries such as semiconductor chips, electric light sources, new energy, etc. It is a strategic resource that is scarce in the world and in short supply in China. In order to solve the "neck" problem of high-purity quartz raw materials, we need to focus on the direction of granitic pegmatite quartz search, and tackle the core technologies of raw material selection and deep de-hybridization to provide support for the development of strategic emerging industries. A granitic pegmatitic quartz from the Altai region of Xinjiang was used as the object of study, and the sample was subjected to deep desmearing using the process of gravity separation -magnetic separation-flotation-acid leaching. The results showed that, firstly, most of the needle iron ore, apatite, calcium alumina garnet and mud were removed by gravity separation, and after magnetic separation to remove iron and flotation to remove mica for gravity separation of intermediate minerals, a high quality sodium feldspar concentrate with a yield of 32.94%, sodium feldspar mineral content of 97.44% and recovery of 74.90% was obtained after one primary feldspar roughing flotation, and a super white feldspar quartz powder with a yield of 3.61% was obtained by primary feldspar sweep flotation. The feldspar sweeping tailings was then selected by primary quartz selection to obtain two products: flotation concentrate and quartz secondary concentrate, among them, the quartz secondary concentrate had a yield of 5.59%, SiO₂ content of 99.61% and SiO₂ recovery of 10.35%, and its composition met the requirements of quartz sand for photovoltaic glass; using the process of calcination-water quenching-acid leaching, the middle-end high-purity quartz sand with yield of 37.32% , SiO₂ content of 99.996% and quartz recovery of 69.52% was obtained from the flotation concentrate. Through this process, both the sodium feldspar resources associated with granite pegmatites were recovered and the quartz in the ore was utilized in a stepwise manner, which not only verified the validity and reliability of the high purity evaluation process, but also pointed out the direction for surveying high purity quartz resources in the Altai region of Xinjiang.