Abstract: Magnetite concentrate is one of the raw materials of iron and steel industry. The removal of harmful impurities sulfur and fluorine is a technical problem faced by mineral processing industry for a long time. This paper summarizes the desulphurization and defluorination technology of high sulfur fluorine magnetite concentrate, especially the application of flotation method in the desulphurization and defluorination process of magnetite concentrate. At the same time, a new method of synchronous reverse flotation desulphurization and defluorination is put forward, and suggestions for future research on desulphurization and defluorination technology of magnetite concentrate are put forward.