Abstract: Vanadium−titanium magnetite resource is a composite mineral resource with iron, vanadium, and titanium as the main metals, and usually accompanied by phosphorus, copper, cobalt, nickel, chromium, scandium, (rare) precious metal elements, and other valuable components, which have very high-value comprehensive utilization. To effectively develop and utilize the vanadium−titanium magnetite resources, this paper introduces the research progress of separation technology and comprehensive utilization of vanadium−titanium magnetite resources from three directions: pre−discarding tailings, beneficiation technology, and comprehensive utilization of vanadium−titanium magnetite concentrate and vanadium−titanium magnetite tailings. The research focus on the development of vanadium−titanium magnetite resources is summarized and prospected.