Abstract: The effects of three commonly associated gangue minerals, such as Muscovite, tourmaline and apatite, on the slurry rheological properties and scheelite flotation indexes of scheelite were studied by slurry rheological test, flotation test of artificial mixed ore and foam stability measurement. Rheological test showed that muscovite in the pulp would form a three-dimensional network structure of edge-face(EF) and edge-edge(EE) combination, which had a large apparent viscosity, while tourmaline and apatite in the pulp was only a simple pile structure, the viscosity was slightly increased. Flotation test and foam stability measurement showed that: In the artificial mixed flotation system of scheelite-muscovite-quartz, with the increase of mass concentration of muscovite, its higher viscosity would increase the half-life and maximum height of the flotation foam, so that the "secondary enrichment" effect was obviously improved, and the flotation index became better within a certain range. However, the higher pulp viscosity would inhibit the collision between bubbles and particles and the fluidity of bubble-particle aggregates, which led to the deterioration of flotation index. In the artificial mixed flotation system of scheelite-tourmaline-quartz, with the increase of metal cations such as Fe³⁺, Mg²⁺ and Ca²⁺ dissolved from tourmaline in water, the flotation of scheelite was inhibited, and the concentrate grade and recovery were reduced. In the artificial mixed flotation system of scheelite-apatite -quartz, adsorption of PO₄³⁻ dissolved from apatite on scheelite surface would lead to surface conversion of minerals, which resulted in similar surface properties of scheelite and apatite, which would worsen the flotation of scheelite. In addition, the addition of tourmaline and apatite had little effect on the stability of foam due to the slow increase of viscosity. The research can provide theoretical basis for the control of slurry rheology and the efficient separation of scheelite and gangue minerals in the process of ore flotation.