Abstract: 75 000-120 000 tons of electrolytic manganese anode slime (EMAS) are produced in the electrolytic manganese industry every year. The EMAS has high content of strategic metals, complex mineral compositions and complicated structure, and thus the comprehensive utilization is difficult. At present, most manufacturers sell the EMAS cheaply or take the stockpiling disposal, causing serious waste of resources and environmental pollution. This paper analyzed the production mechanism and resource characteristics of the EMAS, and also summarized the separation and recovery technologies of the valuable metals including Mn, Pb, Sn, and Se from the EMAS. The advantages and disadvantages of the reduction leaching method, roasting-leaching method, and alkali melting-leaching method were reviewed and compared. This paper puts forward a novel technique solution for the comprehensive recovery of Mn, Pb, Sn, and Se by sulfur conversion, which can provide technical reference for utilization of EMAS.