Abstract: It is difficult to separate and enrichment for micro-fine cassiterite slime with high sulfur and mud in the fine mud system of Bali plant, Guangxi Gaofeng Mining Co., Ltd. An experimental study of recovering tin was carried out. The principle of flotation desulphurization and desliming ─ tin flotation ─ centrifugal gravity separation was determined through the analysis of the flowsheet. Under the condition of the optimal reagent system and technical parameters, the ideal test indicators were obtained with tin grade 26.72% in the tin concentrates and the recovery rate 70.77% of tin in fine mud system. The highly effective recycling technology for micro-fine cassiterite with high sulfur and mud has been industrialized. It breaks through the technical bottleneck of low recovery and enrichment ratio in traditional gravity separation process of fine mud system in Bali plant.