硅藻土特性、提纯及在生物医药领域中的应用

Research Progress on The Properties of Diatomite and Its Application in Biomedical Field

摘要: 基于生物纳米材料的药物和设备在精准治疗和个性化治疗方面具有广阔的应用前景。硅藻土作为战略性非金属矿产，其高比表面积、生物相容性、易于表面修饰、热稳定性、高机械和化学抗性以及低成本的特性，使硅藻土在生物医学应用方面具有极大的潜力。介绍了硅藻土材料的结构、表面化学功能化、生物相容性等特性，综述了硅藻土在生物医学领域的药物传递、生物传感、组织工程和止血剂等方面的应用。

Abstract: Drugs and devices based on bio-nanomaterials have promising applications in precision and personalized therapy. Diatomite, as a strategic nonmetallic mineral, has great potential for biomedical applications due to its high specific surface area, biocompatibility, ease of surface modification, thermal stability, high mechanical and chemical resistance, and low cost. The structural properties, purification, surface chemical functionalization, and biocompatibility of diatomite materials are presented, and the applications of diatomite in biomedical fields such as drug delivery, biosensing, tissue engineering, and hemostatic agents are reviewed.