Abstract: Silicon is a typical harmful impurity in iron ore., So reducing the content of silicon in iron concentrate is always an important topic in iron ore separation.This paper systematically summarizes the research progress of iron ore desilication technology and flotation reagent regime.The research status and development trend of flotation desilication are introduced emphatically.It points out that calcium ion activation-anion reverse flotation of iron ore containing silicon has broad application prospects and how to further improve the selectivity and adaptability of reagents is of great practical significance to the process.