Abstract: The raw ore is mainly fine disseminated hematite and magnetite in Donganshan Sintering Plant. The field problems are low efficiency of ball milling and low monomer dissociation etc. In this research, the process optimization and comparison of magnetic concentrate ball milling and ceramic ball stirring grinding were carried out. The results show that the optimum conditions of stirring mill are as follows: filling rate of 80%, material ball ratio of 0.9, grinding concentration of 60%, medium size of 6 mm and agitator speed of 650 r/min. For ball milling, the optimum conditions are as follows: the medium ratio of 32 mm: 25 mm: 19 mm of 5:3:2, filling rate of 40%, material ball ratio of 1.0, grinding concentration of 70%. And the grinding effect of stirring mill is better. The specific productivity of -0.038 mm is 3 636.20 kg/(m³·h), and the grinding efficiency is 71.93 kg/(kW·h). The analysis of samples with the same fineness shows that the content of superfine and coarser particles is relatively small in stirred mill products, and the dissociation degree of useful mineral monomer is 4.5% ~ 8% higher than that of ball milling. The reverse flotation test shows that the iron grade and recovery rate of concentrate can be increased by 0.94% and 2.99%, respectively. Therefore, agitation mill has better grinding effect and flotation index than ball mill.