Abstract: In order to provide the basis for the mineral evaluation in the detailed investigation stage of the Tibet-Taicangma lead-zinc mine, a detailed process mineralogy study was conducted. The results show that the ore contains 4.2% Pb and 2.81% Zn. The silver, cadmium, selenium, tellurium and strontium are 27 g/t, 0.017%, 0.002%, 0.03% and 0.023%, respectively, which can be comprehensively recycled. Lead exists mainly in the form of galena, and zinc mainly exists in the form of sphalerite. Galena, sphalerite for the comprehensive recovery of minerals. The relationship between lead and zinc minerals is complex and it is in close contact with other minerals. Separation is difficult. The galena inlay grain size is relatively coarse, which is conducive to beneficiation and recovery. The grain size of the sphalerite inlay is fine, and the content below -0.02 mm is as high as 22.07%. It is difficult to be ore dressing and fine grinding work is needed to increase the recovery rate. In addition, gangue minerals are mostly mud-crystal-gray minerals, which are characterized by easy grinding and easy argillization, which will adversely affect the separation of lead and zinc minerals.