Abstract: In order to reduce the dosage of pH regulator and simplify the flotation technological process, a new reagent system had been explored, which Gz92 and AE35 were used for collecting dolomite and quartz in flotation experiments. Through the single mineral experiments and artificial mineral experiments, the collecting and selecting appearance of Gz92 and AE35 were studied. The results showed that Gz92 has strong ability to collect dolomite, and AE35 has strong ability to collect quartz when the pH was 7 as the single collector in the pulp. When Gz92 and AE35 were added in the same pulp, they have strong ability to collect dolomite and quartz, but they have no ability to collect collophanite. In the artificial mixed mineral flotation experiment, the concentrate with P₂O₅ grade 31.91%, recovery of 67.96% can be obtained from the mixed mineral with P₂O₅ grade 18.59%. Based on the above comprehensive analysis, synchronous reserve flotation in nutral pH value was feasible.