Abstract: This study takes a gold-tungsten-tellurium ore in Xiaoqinling area as the research object. Spectral analysis, MLA, EDS, SEM, and other analytical methods were conducted to study process mineralogy, and then the comprehensive utilization test was carried out. The processing mineralogy research shows that the main recoverable elements are Au, W and Te. Pyrite is main carrier of gold and tellurium. The primary gold minerals are native gold and petzite. The main tellurium minerals are petzite, hessite and tellurbismuth. Tungsten is mainly in the form of scheelite. Using the process of preferential flotation of gold and tellurium-recovering tungsten from tailings, a gold tellurium concentrate and a scheelite concentrate with good qualities could be obtained. The Au and Te grade of gold-tellurium concentrate was 44.26 g/t and 148.90 g/t with a recovery of 96.02% and 91.71%, respectively. The WO₃ grade of scheelite concentrate was 33.68% with a recovery of 67.43%. The study provides a technical reference for the comprehensive utilization of mineral resources in Xiaoqinling area.